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Glutathione-doxorubicin conjugate expresses potent cytotoxicity by suppression of glutathione S-transferase activity: comparison between doxorubicin-sensitive and -resistant rat hepatoma cells

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ADH/CYP2E1 and GSH In the hepatocytes, chronic alcohol exposure causes an increase in reduced (GSH) and a decrease in oxidized GSH (GSSG) [48]